Vaccines for prevention of meningococcal disease
نویسندگان
چکیده
منابع مشابه
Vaccines for prevention of group B meningococcal disease: Not your father's vaccines.
For decades, there was no licensed vaccine for prevention of endemic capsular group B meningococcal disease, despite the availability of vaccines for prevention of the other most common meningococcal capsular groups. Recently, however, two new vaccines have been licensed for prevention of group B disease. Although immunogenic and considered to have an acceptable safety profile, there are many s...
متن کاملPrevention of meningococcal disease.
Invasive disease caused by Neisseria meningitidis has an average annual incidence of one case per 100,000 in the United States. The disease can be rapidly fatal or result in severe neurologic and vascular sequelae despite antibiotic therapy. Antibiotic chemoprophylaxis with rifampin, ciprofloxacin, or ceftriaxone is required for household and other close contacts. Although the majority of cases...
متن کاملAn evaluation of emerging vaccines for childhood meningococcal disease
BACKGROUND Meningococcal meningitis is a major cause of disease worldwide, with frequent epidemics particularly affecting an area of sub-Saharan Africa known as the "meningitis belt". Neisseria meningitidis group A (MenA) is responsible for major epidemics in Africa. Recently W-135 has emerged as an important pathogen. Currently, the strategy for control of such outbreaks is emergency use of me...
متن کاملPrevention of meningococcal disease: current use of polysaccharide and conjugate vaccines.
Invasive meningococcal disease (IMD), although uncommon, is difficult to diagnose and can be rapidly fatal, even in healthy young persons. IMD is cyclic, and serogroups responsible for disease vary by age group, although the prevalence of the serogroups changes over time and by geographical location. Two quadrivalent vaccines are licensed in the United States to prevent IMD caused by serogroups...
متن کاملControl of meningococcal meningitis with meningococcal vaccines.
The development of effective meinigococcal vaccines was based upon the finding that immunity to the meningococcus was directly correlated with serum bactericidal antibodies. Purified high molecular weight capsular polysaccharides of serogroups A and C meningococci stimulated the production of humoral antibodies which had group specific bactericidal activity. In controlled field trials in Army...
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ژورنال
عنوان ژورنال: Clinical Microbiology Reviews
سال: 1989
ISSN: 0893-8512,1098-6618
DOI: 10.1128/cmr.2.suppl.s134